Down-regulation of CD4 by memory CD4(+) T cells in vivo renders African green monkeys resistant to progressive SIVagm infection

African green monkeys (genus Chlorocebus) can be infected with SIVagm, but do not develop AIDS. This natural host of SIV, like sooty mangabeys, maintains high levels of SIV replication but has evolved to avoid immunodeficiency. Elucidating the mechanisms that allow the natural hosts to co-exist with...

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Main Authors: Beaumier, Coreen M., Harris, Levelle D., Goldstein, Simoy, Klatt, Nichole R., Whitted, Sonya, McGinty, John, Apetrei, Cristian, Pandrea, Ivona, Hirsch, Vanessa M., Brenchley, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723181/
https://ncbi.nlm.nih.gov/pubmed/19525963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1970
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