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Cytotoxic T cell functions accumulate when CD4 is downregulated by CD4(+) T cells in African green monkeys()
African green monkeys (AGMs) are a natural host of simian immunodeficiency virus (SIVagm) that do not develop simian AIDS. Adult AGMs naturally have low numbers of CD4(+) T cells and a large population of MHC Class II-restricted CD8αα T cells that are generated through CD4 down-regulation in CD4(+)...
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Publicado no: | J Immunol |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502537/ https://ncbi.nlm.nih.gov/pubmed/28438898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700136 |
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