Hypoxia injures endothelial cells by increasing endogenous xanthine oxidase activity.

Exposure to decreasing oxygen tensions progressively increased xanthine dehydrogenase (XD) and xanthine oxidase (XO) activities over 48 hr in cultured pulmonary artery endothelial cells (EC) without altering XD/XO ratios. Increases in XD and XO activity in EC induced by hypoxia were associated upon...

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Detalhes bibliográficos
Main Authors: Terada, L S, Guidot, D M, Leff, J A, Willingham, I R, Hanley, M E, Piermattei, D, Repine, J E
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC48867/
https://ncbi.nlm.nih.gov/pubmed/1314387
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