Hypoxia injures endothelial cells by increasing endogenous xanthine oxidase activity.

Exposure to decreasing oxygen tensions progressively increased xanthine dehydrogenase (XD) and xanthine oxidase (XO) activities over 48 hr in cultured pulmonary artery endothelial cells (EC) without altering XD/XO ratios. Increases in XD and XO activity in EC induced by hypoxia were associated upon...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Terada, L S, Guidot, D M, Leff, J A, Willingham, I R, Hanley, M E, Piermattei, D, Repine, J E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48867/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1314387/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.8.3362
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