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Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits.

Reactive oxygen species play a central role in vascular inflammation and atherogenesis, with enhanced superoxide (O2.-) production contributing significantly to impairment of nitric oxide (.NO)-dependent relaxation of vessels from cholesterol-fed rabbits. We investigated potential sources of O2.- pr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: White, C R, Darley-Usmar, V, Berrington, W R, McAdams, M, Gore, J Z, Thompson, J A, Parks, D A, Tarpey, M M, Freeman, B A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38744/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8710942/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.16.8745
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