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Sequential activation of JAKs, STATs and xanthine dehydrogenase/oxidase by hypoxia in lung microvascular endothelial cells

Xanthine dehydrogenase/oxidase (XDH/XO) is associated with various pathological conditions related to the endothelial injury. However, the molecular mechanism underlying the activation of XDH/XO by hypoxia remains largely unknown. In this report, we determined whether the Janus kinases (JAKs) and si...

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Autors principals: Wang, Guansong, Qian, Pin, Jackson, Fannie R., Qian, Guisheng, Wu, Guangyu
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276459/
https://ncbi.nlm.nih.gov/pubmed/17920330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2007.08.008
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