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Xanthine Oxidase Inhibition Attenuates Endothelial Dysfunction Caused by Chronic Intermittent Hypoxia in Rats

BACKGROUND: Xanthine oxidase is a major source of superoxide in the vascular endothelium. Previous work in humans demonstrated improved conduit artery function following xanthine oxidase inhibition in patients with obstructive sleep apnea. Objectives: To determine whether impairments in endothelium-...

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Detalhes bibliográficos
Main Authors: Dopp, John M., Philippi, Nathan R., Marcus, Noah J., Olson, E. Burt, Bird, Cynthia E., Moran, John J.M., Mueller, Scott W., Morgan, Barbara J.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214835/
https://ncbi.nlm.nih.gov/pubmed/21846958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329341
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