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Influence of Intermittent Hypoxia on Myocardial and Hepatic P-glycoprotein Expression

STUDY OBJECTIVE: The purpose of this study was to determine if intermittent hypoxia that mimics obstructive sleep apnea would upregulate myocardial and hepatic p-glycoprotein protein and Abcb1a/Abcb1b mRNA expression. DESIGN: Prospective, randomized, blinded, parallel designed animal study SETTING:...

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Detalhes bibliográficos
Main Authors: Dopp, John M., Moran, John J., Abel, Nicole J., Wiegert, Nicholas A., Cowgill, John B., Olson, E. Burt, Sims, J. Jason
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873206/
https://ncbi.nlm.nih.gov/pubmed/19323616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1592/phco.29.4.365
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