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A Novel Complotype Combination Associates with Age-Related Macular Degeneration and High Complement Activation Levels in vivo

The complement system is the first line of defense against foreign intruders, and deregulation of this system has been described in multiple diseases. In age-related macular degeneration (AMD), patients have higher complement activation levels compared to controls. Recently, a combination of three s...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Paun, Constantin C., Lechanteur, Yara T. E., Groenewoud, Joannes M. M., Altay, Lebriz, Schick, Tina, Daha, Mohamed R., Fauser, Sascha, Hoyng, Carel B., den Hollander, Anneke I., de Jong, Eiko K.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886525/
https://ncbi.nlm.nih.gov/pubmed/27241480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26568
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