A Novel Complotype Combination Associates with Age-Related Macular Degeneration and High Complement Activation Levels in vivo

The complement system is the first line of defense against foreign intruders, and deregulation of this system has been described in multiple diseases. In age-related macular degeneration (AMD), patients have higher complement activation levels compared to controls. Recently, a combination of three s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Paun, Constantin C., Lechanteur, Yara T. E., Groenewoud, Joannes M. M., Altay, Lebriz, Schick, Tina, Daha, Mohamed R., Fauser, Sascha, Hoyng, Carel B., den Hollander, Anneke I., de Jong, Eiko K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886525/
https://ncbi.nlm.nih.gov/pubmed/27241480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26568
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