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Analysis of Risk Alleles and Complement Activation Levels in Familial and Non-Familial Age-Related Macular Degeneration

AIMS: Age-related macular degeneration (AMD) is a multifactorial disease, in which complement-mediated inflammation plays a pivotal role. A positive family history is an important risk factor for developing AMD. Certain lifestyle factors are shown to be significantly associated with AMD in non-famil...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Saksens, Nicole T. M., Lechanteur, Yara T. E., Verbakel, Sanne K., Groenewoud, Joannes M. M., Daha, Mohamed R., Schick, Tina, Fauser, Sascha, Boon, Camiel J. F., Hoyng, Carel B., den Hollander, Anneke I.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892537/
https://ncbi.nlm.nih.gov/pubmed/27258093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144367
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