Analysis of Risk Alleles and Complement Activation Levels in Familial and Non-Familial Age-Related Macular Degeneration

AIMS: Age-related macular degeneration (AMD) is a multifactorial disease, in which complement-mediated inflammation plays a pivotal role. A positive family history is an important risk factor for developing AMD. Certain lifestyle factors are shown to be significantly associated with AMD in non-famil...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Saksens, Nicole T. M., Lechanteur, Yara T. E., Verbakel, Sanne K., Groenewoud, Joannes M. M., Daha, Mohamed R., Schick, Tina, Fauser, Sascha, Boon, Camiel J. F., Hoyng, Carel B., den Hollander, Anneke I.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892537/
https://ncbi.nlm.nih.gov/pubmed/27258093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144367
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