Analysis of Risk Alleles and Complement Activation Levels in Familial and Non-Familial Age-Related Macular Degeneration

AIMS: Age-related macular degeneration (AMD) is a multifactorial disease, in which complement-mediated inflammation plays a pivotal role. A positive family history is an important risk factor for developing AMD. Certain lifestyle factors are shown to be significantly associated with AMD in non-famil...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Saksens, Nicole T. M., Lechanteur, Yara T. E., Verbakel, Sanne K., Groenewoud, Joannes M. M., Daha, Mohamed R., Schick, Tina, Fauser, Sascha, Boon, Camiel J. F., Hoyng, Carel B., den Hollander, Anneke I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892537/
https://ncbi.nlm.nih.gov/pubmed/27258093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144367
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