A Novel Complotype Combination Associates with Age-Related Macular Degeneration and High Complement Activation Levels in vivo

The complement system is the first line of defense against foreign intruders, and deregulation of this system has been described in multiple diseases. In age-related macular degeneration (AMD), patients have higher complement activation levels compared to controls. Recently, a combination of three s...

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Publicado en:Sci Rep
Autores principales: Paun, Constantin C., Lechanteur, Yara T. E., Groenewoud, Joannes M. M., Altay, Lebriz, Schick, Tina, Daha, Mohamed R., Fauser, Sascha, Hoyng, Carel B., den Hollander, Anneke I., de Jong, Eiko K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886525/
https://ncbi.nlm.nih.gov/pubmed/27241480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26568
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