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Nanoparticle Delivered Human Biliverdin Reductase-Based Peptide Increases Glucose Uptake by Activating IRK/Akt/GSK3 Axis: The Peptide Is Effective in the Cell and Wild-Type and Diabetic Ob/Ob Mice
Insulin's stimulation of glucose uptake by binding to the IRK extracellular domain is compromised in diabetes. We have recently described an unprecedented approach to stimulating glucose uptake. KYCCSRK (P2) peptide, corresponding to the C-terminal segment of hBVR, was effective in binding to a...
Zapisane w:
Wydane w: | J Diabetes Res |
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Główni autorzy: | , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
Hindawi Publishing Corporation
2016
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886063/ https://ncbi.nlm.nih.gov/pubmed/27294151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4712053 |
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