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Development of a CART Model to Predict the Synthesis of Cardiotoxic Daunorubicinol in Heart Tissue Samples from Donors with and without Down Syndrome

Daunorubicin (DAUN) and doxorubicin (DOX) are used to treat a variety of cancers. The use of DAUN and DOX is hampered by the development of cardiotoxicity. Clinical evidence suggests that patients with leukemia and Down syndrome (DS) are at increased risk for anthracycline-related cardiotoxicity. Ca...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Pharm Sci
Egile Nagusiak: Hoefer, Carrie C., Blair, Rachael Hageman, Blanco, Javier G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885781/
https://ncbi.nlm.nih.gov/pubmed/27112290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2016.03.013
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