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Interindividual Variability in the Cardiac Expression of Anthracycline Reductases in Donors with- and without- Down Syndrome
PURPOSE: The intracardiac synthesis of anthracycline alcohol metabolites (e.g., daunorubicinol) contributes to the pathogenesis of anthracycline-related cardiotoxicity. Cancer patients with Down syndrome (DS) are at increased risk for anthracycline-related cardiotoxicity. We profiled the expression...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065192/ https://ncbi.nlm.nih.gov/pubmed/24562808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1267-1 |
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