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Development of a CART Model to Predict the Synthesis of Cardiotoxic Daunorubicinol in Heart Tissue Samples from Donors with and without Down Syndrome

Daunorubicin (DAUN) and doxorubicin (DOX) are used to treat a variety of cancers. The use of DAUN and DOX is hampered by the development of cardiotoxicity. Clinical evidence suggests that patients with leukemia and Down syndrome (DS) are at increased risk for anthracycline-related cardiotoxicity. Ca...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Pharm Sci
Main Authors: Hoefer, Carrie C., Blair, Rachael Hageman, Blanco, Javier G.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885781/
https://ncbi.nlm.nih.gov/pubmed/27112290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2016.03.013
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