Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase

Cryo-electron microscopy (cryo-EM) methods are now being used to determine structures at near-atomic resolution and have great promise in molecular pharmacology, especially in the context of mapping the binding of small-molecule ligands to protein complexes that display conformational flexibility. W...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Borgnia, Mario J., Banerjee, Soojay, Merk, Alan, Matthies, Doreen, Bartesaghi, Alberto, Rao, Prashant, Pierson, Jason, Earl, Lesley A., Falconieri, Veronica, Subramaniam, Sriram, Milne, Jacqueline L. S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Accelerated Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885502/
https://ncbi.nlm.nih.gov/pubmed/27036132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.103382
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados