Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase

Cryo-electron microscopy (cryo-EM) methods are now being used to determine structures at near-atomic resolution and have great promise in molecular pharmacology, especially in the context of mapping the binding of small-molecule ligands to protein complexes that display conformational flexibility. W...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Pharmacol
Egile Nagusiak: Borgnia, Mario J., Banerjee, Soojay, Merk, Alan, Matthies, Doreen, Bartesaghi, Alberto, Rao, Prashant, Pierson, Jason, Earl, Lesley A., Falconieri, Veronica, Subramaniam, Sriram, Milne, Jacqueline L. S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2016
Gaiak:
Accelerated Communication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885502/
https://ncbi.nlm.nih.gov/pubmed/27036132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.103382
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