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Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression

The prognosis of patients with metastatic breast cancer remains poor, and thus novel therapeutic approaches are needed. Capecitabine, which is commonly used for metastatic breast cancer in different settings, is an inactive prodrug that takes advantage of elevated levels of thymidine phosphorylase (...

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發表在:Oncotarget
Main Authors: Terranova-Barberio, Manuela, Roca, Maria Serena, Zotti, Andrea Ilaria, Leone, Alessandra, Bruzzese, Francesca, Vitagliano, Carlo, Scogliamiglio, Giosuè, Russo, Domenico, D'Angelo, Giovanni, Franco, Renato, Budillon, Alfredo, Di Gennaro, Elena
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884949/
https://ncbi.nlm.nih.gov/pubmed/26735339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6802
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