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Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase
BACKGROUND: Potentiation of anticancer activity of capecitabine is required to improve its therapeutic index. In colorectal cancer (CRC) cells, we evaluated whether the histone deacetylase-inhibitor vorinostat may induce synergistic antitumour effects in combination with capecitabine by modulating t...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2994231/ https://ncbi.nlm.nih.gov/pubmed/21045833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605969 |
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