Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53

BACKGROUND: Recurrence with distant metastases has become the predominant pattern of failure in locally advanced rectal cancer (LARC), thus the integration of new antineoplastic agents into preoperative fluoropyrimidine-based chemo-radiotherapy represents a clinical challenge to implement an intensi...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Terranova-Barberio, Manuela, Pecori, Biagio, Roca, Maria Serena, Imbimbo, Serena, Bruzzese, Francesca, Leone, Alessandra, Muto, Paolo, Delrio, Paolo, Avallone, Antonio, Budillon, Alfredo, Di Gennaro, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719792/
https://ncbi.nlm.nih.gov/pubmed/29212503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0647-5
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