Tissue transglutaminase: a new target to reverse cancer drug resistance

by Budillon, Alfredo, Carbone, Carmine, Di Gennaro, Elena
Published 2011

Implication for Cancer Stem Cells in Solid Cancer Chemo-Resistance: Promising Therapeutic Strategies Based on the Use of HDAC Inhibitors

by Roca, Maria Serena, Di Gennaro, Elena, Budillon, Alfredo
Published in J Clin Med (2019)

Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53

by Terranova-Barberio, Manuela, Pecori, Biagio, Roca, Maria Serena, Imbimbo, Serena, Bruzzese, Francesca, Leone, Alessandra, Muto, Paolo, Delrio, Paolo, Avallone, Antonio, Budillon, Alfredo, Di Gennaro, Elena
Published in J Exp Clin Cancer Res (2017)

Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression

by Terranova-Barberio, Manuela, Roca, Maria Serena, Zotti, Andrea Ilaria, Leone, Alessandra, Bruzzese, Francesca, Vitagliano, Carlo, Scogliamiglio, Giosuè, Russo, Domenico, D'Angelo, Giovanni, Franco, Renato, Budillon, Alfredo, Di Gennaro, Elena
Published in Oncotarget (2015)

HSP90 identified by a proteomic approach as druggable target to reverse platinum resistance in ovarian cancer

by Lombardi, Rita, Sonego, Maura, Pucci, Biagio, Addi, Laura, Iannelli, Federica, Capone, Francesca, Alfano, Luigi, Roca, Maria Serena, Milone, Maria Rita, Moccia, Tania, Costa, Alice, Di Gennaro, Elena, Bruzzese, Francesca, Baldassarre, Gustavo, Budillon, Alfredo
Published in Mol Oncol (2021)

Synergistic antitumor interaction of valproic acid and simvastatin sensitizes prostate cancer to docetaxel by targeting CSCs compartment via YAP inhibition

by Iannelli, Federica, Roca, Maria Serena, Lombardi, Rita, Ciardiello, Chiara, Grumetti, Laura, De Rienzo, Simona, Moccia, Tania, Vitagliano, Carlo, Sorice, Angela, Costantini, Susan, Milone, Maria Rita, Pucci, Biagio, Leone, Alessandra, Di Gennaro, Elena, Mancini, Rita, Ciliberto, Gennaro, Bruzzese, Francesca, Budillon, Alfredo
Published in J Exp Clin Cancer Res (2020)

Valproic Acid Synergizes With Cisplatin and Cetuximab in vitro and in vivo in Head and Neck Cancer by Targeting the Mechanisms of Resistance

by Iannelli, Federica, Zotti, Andrea Ilaria, Roca, Maria Serena, Grumetti, Laura, Lombardi, Rita, Moccia, Tania, Vitagliano, Carlo, Milone, Maria Rita, Ciardiello, Chiara, Bruzzese, Francesca, Leone, Alessandra, Cavalcanti, Ernesta, De Cecio, Rossella, Iachetta, Giuseppina, Valiante, Salvatore, Ionna, Franco, Caponigro, Francesco, Di Gennaro, Elena, Budillon, Alfredo
Published in Front Cell Dev Biol (2020)

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

by Ciardiello, Chiara, Leone, Alessandra, Lanuti, Paola, Roca, Maria S., Moccia, Tania, Minciacchi, Valentina R., Minopoli, Michele, Gigantino, Vincenzo, De Cecio, Rossella, Rippa, Massimo, Petti, Lucia, Capone, Francesca, Vitagliano, Carlo, Milone, Maria R., Pucci, Biagio, Lombardi, Rita, Iannelli, Federica, Di Gennaro, Elena, Bruzzese, Francesca, Marchisio, Marco, Carriero, Maria V., Di Vizio, Dolores, Budillon, Alfredo
Published in J Exp Clin Cancer Res (2019)

Effect of Bevacizumab in Combination With Standard Oxaliplatin-Based Regimens in Patients With Metastatic Colorectal Cancer: A Randomized Clinical Trial

by Avallone, Antonio, Piccirillo, Maria C., Nasti, Guglielmo, Rosati, Gerardo, Carlomagno, Chiara, Di Gennaro, Elena, Romano, Carmela, Tatangelo, Fabiana, Granata, Vincenza, Cassata, Antonino, Silvestro, Lucrezia, De Stefano, Alfonso, Aloj, Luigi, Vicario, Valeria, Nappi, Anna, Leone, Alessandra, Bilancia, Domenico, Arenare, Laura, Petrillo, Antonella, Lastoria, Secondo, Gallo, Ciro, Botti, Gerardo, Delrio, Paolo, Izzo, Francesco, Perrone, Franco, Budillon, Alfredo
Published in JAMA Netw Open (2021)

Randomized phase II study of valproic acid in combination with bevacizumab and oxaliplatin/fluoropyrimidine regimens in patients with RAS-mutated metastatic colorectal cancer: the...

by Avallone, Antonio, Piccirillo, Maria Carmela, Di Gennaro, Elena, Romano, Carmela, Calabrese, Filomena, Roca, Maria Serena, Tatangelo, Fabiana, Granata, Vincenza, Cassata, Antonio, Cavalcanti, Ernesta, Maurea, Nicola, Maiolino, Piera, Silvestro, Lucrezia, De Stefano, Alfonso, Giuliani, Francesco, Rosati, Gerardo, Tamburini, Emiliano, Aprea, Pasquale, Vicario, Valeria, Nappi, Anna, Vitagliano, Carlo, Casaretti, Rossana, Leone, Alessandra, Petrillo, Antonella, Botti, Gerardo, Delrio, Paolo, Izzo, Francesco, Perrone, Francesco, Budillon, Alfredo
Published in Ther Adv Med Oncol (2020)

Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid - short Radi...

by Avallone, Antonio, Piccirillo, Maria Carmela, Delrio, Paolo, Pecori, Biagio, Di Gennaro, Elena, Aloj, Luigi, Tatangelo, Fabiana, D’Angelo, Valentina, Granata, Cinzia, Cavalcanti, Ernesta, Maurea, Nicola, Maiolino, Piera, Bianco, Franco, Montano, Massimo, Silvestro, Lucrezia, Terranova Barberio, Manuela, Roca, Maria Serena, Di Maio, Massimo, Marone, Pietro, Botti, Gerardo, Petrillo, Antonella, Daniele, Gennaro, Lastoria, Secondo, Iaffaioli, Vincenzo R, Romano, Giovanni, Caracò, Corradina, Muto, Paolo, Gallo, Ciro, Perrone, Francesco, Budillon, Alfredo
Published in BMC Cancer (2014)

Phase II clinical study of valproic acid plus cisplatin and cetuximab in recurrent and/or metastatic squamous cell carcinoma of Head and Neck-V-CHANCE trial

by Caponigro, Francesco, Di Gennaro, Elena, Ionna, Franco, Longo, Francesco, Aversa, Corrado, Pavone, Ettore, Maglione, Maria Grazia, Di Marzo, Massimiliano, Muto, Paolo, Cavalcanti, Ernesta, Petrillo, Antonella, Sandomenico, Fabio, Maiolino, Piera, D’Aniello, Roberta, Botti, Gerardo, De Cecio, Rossella, Losito, Nunzia Simona, Scala, Stefania, Trotta, Annamaria, Zotti, Andrea Ilaria, Bruzzese, Francesca, Daponte, Antonio, Calogero, Ester, Montano, Massimo, Pontone, Monica, De Feo, Gianfranco, Perri, Francesco, Budillon, Alfredo
Published in BMC Cancer (2016)

A randomized phase 3 study on the optimization of the combination of bevacizumab with FOLFOX/OXXEL in the treatment of patients with metastatic colorectal cancer-OBELICS (Optimizat...

by Avallone, Antonio, Piccirillo, Maria Carmela, Aloj, Luigi, Nasti, Guglielmo, Delrio, Paolo, Izzo, Francesco, Di Gennaro, Elena, Tatangelo, Fabiana, Granata, Vincenza, Cavalcanti, Ernesta, Maiolino, Piera, Bianco, Francesco, Aprea, Pasquale, De Bellis, Mario, Pecori, Biagio, Rosati, Gerardo, Carlomagno, Chiara, Bertolini, Alessandro, Gallo, Ciro, Romano, Carmela, Leone, Alessandra, Caracò, Corradina, de Lutio di Castelguidone, Elisabetta, Daniele, Gennaro, Catalano, Orlando, Botti, Gerardo, Petrillo, Antonella, Romano, Giovanni M., Iaffaioli, Vincenzo R., Lastoria, Secondo, Perrone, Francesco, Budillon, Alfredo
Published in BMC Cancer (2016)

A standardized flow cytometry network study for the assessment of circulating endothelial cell physiological ranges

by Lanuti, Paola, Simeone, Pasquale, Rotta, Gianluca, Almici, Camillo, Avvisati, Giuseppe, Azzaro, Rosa, Bologna, Giuseppina, Budillon, Alfredo, Di Cerbo, Melania, Di Gennaro, Elena, Di Martino, Maria Luisa, Diodato, Annamaria, Doretto, Paolo, Ercolino, Eva, Falda, Alessandra, Gregorj, Chiara, Leone, Alessandra, Losa, Francesca, Malara, Natalia, Marini, Mirella, Mastroroberto, Pasquale, Mollace, Vincenzo, Morelli, Michele, Muggianu, Emma, Musolino, Giuseppe, Neva, Arabella, Pierdomenico, Laura, Pinna, Silvia, Piovani, Giovanna, Roca, Maria Serena, Russo, Domenico, Scotti, Lorenza, Tirindelli, Maria Cristina, Trunzo, Valentina, Venturella, Roberta, Vitagliano, Carlo, Zullo, Fulvio, Marchisio, Marco, Miscia, Sebastiano
Published in Sci Rep (2018)