Ładuje się......
Crosstalk between Ca(2+) signaling and mitochondrial H(2)O(2) is required for rotenone inhibition of mTOR signaling pathway leading to neuronal apoptosis
Rotenone, a neurotoxic pesticide, induces loss of dopaminergic neurons related to Parkinson's disease. Previous studies have shown that rotenone induces neuronal apoptosis partly by triggering hydrogen peroxide (H(2)O(2))-dependent suppression of mTOR pathway. However, the underlying mechanism...
Zapisane w:
| Wydane w: | Oncotarget |
|---|---|
| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Impact Journals LLC
2016
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4884936/ https://ncbi.nlm.nih.gov/pubmed/26859572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7183 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|