Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74

Pathologic proliferation of mesangial and parietal epithelial cells (PECs) is a hallmark of various glomerulonephritides. Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that mediates inflammation by engagement of a receptor complex involving the components CD74, CD44, CXCR2,...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Main Authors: Djudjaj, Sonja, Lue, Hongqi, Rong, Song, Papasotiriou, Marios, Klinkhammer, Barbara M., Zok, Stephanie, Klaener, Ole, Braun, Gerald S., Lindenmeyer, Maja T., Cohen, Clemens D., Bucala, Richard, Tittel, Andre P., Kurts, Christian, Moeller, Marcus J., Floege, Juergen, Ostendorf, Tammo, Bernhagen, Jürgen, Boor, Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2016
Assuntos:
Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884103/
https://ncbi.nlm.nih.gov/pubmed/26453615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015020149
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