Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74

Pathologic proliferation of mesangial and parietal epithelial cells (PECs) is a hallmark of various glomerulonephritides. Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that mediates inflammation by engagement of a receptor complex involving the components CD74, CD44, CXCR2,...

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Bibliografski detalji
Izdano u:J Am Soc Nephrol
Glavni autori: Djudjaj, Sonja, Lue, Hongqi, Rong, Song, Papasotiriou, Marios, Klinkhammer, Barbara M., Zok, Stephanie, Klaener, Ole, Braun, Gerald S., Lindenmeyer, Maja T., Cohen, Clemens D., Bucala, Richard, Tittel, Andre P., Kurts, Christian, Moeller, Marcus J., Floege, Juergen, Ostendorf, Tammo, Bernhagen, Jürgen, Boor, Peter
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2016
Teme:
Basic Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884103/
https://ncbi.nlm.nih.gov/pubmed/26453615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015020149
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