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A functional heteromeric MIF receptor formed by CD74 and CXCR4

MIF is a chemokine-like inflammatory mediator that triggers leukocyte recruitment by binding to CXCR2 and CXCR4. MIF also interacts with CD74/invariant chain, a single-pass membrane-receptor. We identified complexes between CD74 and CXCR2 with a role in leukocyte recruitment. It is unknown whether C...

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Detalhes bibliográficos
Main Authors: Schwartz, Verena, Lue, Hongqi, Kraemer, Sandra, Korbiel, Joanna, Krohn, Regina, Ohl, Kim, Bucala, Richard, Weber, Christian, Bernhagen, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911026/
https://ncbi.nlm.nih.gov/pubmed/19665027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.07.058
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