A functional heteromeric MIF receptor formed by CD74 and CXCR4

MIF is a chemokine-like inflammatory mediator that triggers leukocyte recruitment by binding to CXCR2 and CXCR4. MIF also interacts with CD74/invariant chain, a single-pass membrane-receptor. We identified complexes between CD74 and CXCR2 with a role in leukocyte recruitment. It is unknown whether C...

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Bibliografiske detaljer
Main Authors:	Schwartz, Verena, Lue, Hongqi, Kraemer, Sandra, Korbiel, Joanna, Krohn, Regina, Ohl, Kim, Bucala, Richard, Weber, Christian, Bernhagen, Jürgen
Format:	Artigo
Sprog:	Inglês
Udgivet:	2009
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2911026/ https://ncbi.nlm.nih.gov/pubmed/19665027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.07.058
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A functional heteromeric MIF receptor formed by CD74 and CXCR4

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