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Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment

We have recently identified the archaic cytokine macrophage migration inhibitory factor (MIF) as a non-canonical ligand of the CXC chemokine receptors CXCR2 and CXCR4 in inflammatory and atherogenic cell recruitment. Because its affinity for CXCR2 was particularly high, we hypothesized that MIF may...

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Main Authors: Weber, Christian, Kraemer, Sandra, Drechsler, Maik, Lue, Hongqi, Koenen, Rory R., Kapurniotu, Aphrodite, Zernecke, Alma, Bernhagen, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566990/
https://ncbi.nlm.nih.gov/pubmed/18852457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804017105
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