Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74

Pathologic proliferation of mesangial and parietal epithelial cells (PECs) is a hallmark of various glomerulonephritides. Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that mediates inflammation by engagement of a receptor complex involving the components CD74, CD44, CXCR2,...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Djudjaj, Sonja, Lue, Hongqi, Rong, Song, Papasotiriou, Marios, Klinkhammer, Barbara M., Zok, Stephanie, Klaener, Ole, Braun, Gerald S., Lindenmeyer, Maja T., Cohen, Clemens D., Bucala, Richard, Tittel, Andre P., Kurts, Christian, Moeller, Marcus J., Floege, Juergen, Ostendorf, Tammo, Bernhagen, Jürgen, Boor, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2016
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884103/
https://ncbi.nlm.nih.gov/pubmed/26453615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015020149
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