Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74

Pathologic proliferation of mesangial and parietal epithelial cells (PECs) is a hallmark of various glomerulonephritides. Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that mediates inflammation by engagement of a receptor complex involving the components CD74, CD44, CXCR2,...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Djudjaj, Sonja, Lue, Hongqi, Rong, Song, Papasotiriou, Marios, Klinkhammer, Barbara M., Zok, Stephanie, Klaener, Ole, Braun, Gerald S., Lindenmeyer, Maja T., Cohen, Clemens D., Bucala, Richard, Tittel, Andre P., Kurts, Christian, Moeller, Marcus J., Floege, Juergen, Ostendorf, Tammo, Bernhagen, Jürgen, Boor, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884103/
https://ncbi.nlm.nih.gov/pubmed/26453615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015020149
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