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IL-6 Trans-Signaling Drives Murine Crescentic GN
The role of IL-6 signaling in renal diseases remains controversial, with data describing both anti-inflammatory and proinflammatory effects. IL-6 can act via classic signaling, engaging its two membrane receptors gp130 and IL-6 receptor (IL-6R). Alternatively, IL-6 trans-signaling requires soluble I...
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| Publicado no: | J Am Soc Nephrol |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4696576/ https://ncbi.nlm.nih.gov/pubmed/26041841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014111147 |
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