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AbDesign: an algorithm for combinatorial backbone design guided by natural conformations and sequences

Computational design of protein function has made substantial progress, generating new enzymes, binders, inhibitors, and nanomaterials not previously seen in nature. However, the ability to design new protein backbones for function – essential to exert control over all polypeptide degrees of freedom...

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Detalles Bibliográficos
Publicado en:Proteins
Main Authors: Lapidoth, Gideon D., Baran, Dror, Pszolla, Gabriele M., Norn, Christoffer, Alon, Assaf, Tyka, Michael D., Fleishman, Sarel J.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881815/
https://ncbi.nlm.nih.gov/pubmed/25670500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24779
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