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AbDesign: an algorithm for combinatorial backbone design guided by natural conformations and sequences

Computational design of protein function has made substantial progress, generating new enzymes, binders, inhibitors, and nanomaterials not previously seen in nature. However, the ability to design new protein backbones for function – essential to exert control over all polypeptide degrees of freedom...

Полное описание

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Библиографические подробности
Опубликовано в: :Proteins
Главные авторы: Lapidoth, Gideon D., Baran, Dror, Pszolla, Gabriele M., Norn, Christoffer, Alon, Assaf, Tyka, Michael D., Fleishman, Sarel J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881815/
https://ncbi.nlm.nih.gov/pubmed/25670500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24779
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