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Is the Efficiency of RNA Silencing Evolutionarily Regulated?

Small interfering RNAs (siRNAs) and microRNAs (miRNAs) regulate gene expression in a sequence-specific manner. Genes with partial complementarity to siRNA/miRNA sequences in their 3′-untranslated regions (UTRs) are suppressed by a mechanism referred to as the siRNA off-target effect or miRNA-mediate...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Glavni avtor: Ui-Tei, Kumiko
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881541/
https://ncbi.nlm.nih.gov/pubmed/27187367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050719
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