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Thermodynamic Control of Small RNA-Mediated Gene Silencing
Small interfering RNAs (siRNAs) and microRNAs (miRNAs) are key regulators of posttranscriptional gene silencing, which is referred to as RNA interference (RNAi) or RNA silencing. In RNAi, siRNA loaded onto the RNA-induced silencing complex (RISC) downreugulates target gene expression by cleaving mRN...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Research Foundation
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366367/ https://ncbi.nlm.nih.gov/pubmed/22675333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00101 |
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