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Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus
GW182 family proteins play important roles in microRNA (miRNA)-mediated gene silencing. They interact with Argonaute (Ago) proteins and localize in processing bodies, which are cytoplasmic foci involved in mRNA degradation and storage. Here, we demonstrated that human GW182 paralog, TNRC6A, is a nuc...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527724/ https://ncbi.nlm.nih.gov/pubmed/23150874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.034769.112 |
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