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Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus
GW182 family proteins play important roles in microRNA (miRNA)-mediated gene silencing. They interact with Argonaute (Ago) proteins and localize in processing bodies, which are cytoplasmic foci involved in mRNA degradation and storage. Here, we demonstrated that human GW182 paralog, TNRC6A, is a nuc...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527724/ https://ncbi.nlm.nih.gov/pubmed/23150874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.034769.112 |
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