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Is the Efficiency of RNA Silencing Evolutionarily Regulated?
Small interfering RNAs (siRNAs) and microRNAs (miRNAs) regulate gene expression in a sequence-specific manner. Genes with partial complementarity to siRNA/miRNA sequences in their 3′-untranslated regions (UTRs) are suppressed by a mechanism referred to as the siRNA off-target effect or miRNA-mediate...
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Publicado no: | Int J Mol Sci |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4881541/ https://ncbi.nlm.nih.gov/pubmed/27187367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050719 |
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