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A-to-I editing in the miRNA seed region regulates target mRNA selection and silencing efficiency
Hydrolytic deamination of adenosine to inosine (A-to-I) by adenosine deaminases acting on RNA (ADARs) is a post-transcriptional modification which results in a discrepancy between genomic DNA and the transcribed RNA sequence, thus contributing to the diversity of the transcriptome. Inosine preferent...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150774/ https://ncbi.nlm.nih.gov/pubmed/25056317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku662 |
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