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E-Cadherin Is Transcriptionally Activated via Suppression of ZEB1 Transcriptional Repressor by Small RNA-Mediated Gene Silencing

RNA activation has been reported to be induced by small interfering RNAs (siRNAs) that act on the promoters of several genes containing E-cadherin. In this study, we present an alternative mechanism of E-cadherin activation in human PC-3 cells by siRNAs previously reported to possess perfect-complem...

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Hlavní autoři: Mazda, Minami, Nishi, Kenji, Naito, Yuki, Ui-Tei, Kumiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244408/
https://ncbi.nlm.nih.gov/pubmed/22205962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028688
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