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Inhibition of Toll-Like Receptor 4 Signaling Mitigates Microvascular Loss but Not Fibrosis in a Model of Ischemic Acute Kidney Injury

The development of chronic kidney disease (CKD) following an episode of acute kidney injury (AKI) is an increasingly recognized clinical problem. Inhibition of toll-like receptor 4 (TLR4) protects renal function in animal models of AKI and has become a viable therapeutic strategy in AKI. However, th...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Dagher, Pierre C., Hato, Takashi, Mang, Henry E., Plotkin, Zoya, Richardson, Quentin V., Massad, Michael, Mai, Erik, Kuehl, Sarah E., Graham, Paige, Kumar, Rakesh, Sutton, Timothy A.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881473/
https://ncbi.nlm.nih.gov/pubmed/27136544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050647
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