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MMP-9 gene deletion mitigates microvascular loss in a model of ischemic acute kidney injury

Microvascular rarefaction following an episode of acute kidney injury (AKI) is associated with renal hypoxia and progression toward chronic kidney disease. The mechanisms contributing to microvascular rarefaction are not well-understood, although disruption in local angioregulatory substances is tho...

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Detalhes bibliográficos
Main Authors: Lee, So-Young, Hörbelt, Markus, Mang, Henry E., Knipe, Nicole L., Bacallao, Robert L., Sado, Yoshikazu, Sutton, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129879/
https://ncbi.nlm.nih.gov/pubmed/21454251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00445.2010
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