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Histone acetyltransferases: challenges in targeting bi-substrate enzymes

Histone acetyltransferases (HATs) are epigenetic enzymes that install acetyl groups onto lysine residues of cellular proteins such as histones, transcription factors, nuclear receptors, and enzymes. HATs have been shown to play a role in diseases ranging from cancer and inflammatory diseases to neur...

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Podrobná bibliografie
Vydáno v:Clin Epigenetics
Hlavní autoři: Wapenaar, Hannah, Dekker, Frank J.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881052/
https://ncbi.nlm.nih.gov/pubmed/27231488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0225-2
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