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Histone acetyltransferases: challenges in targeting bi-substrate enzymes

Histone acetyltransferases (HATs) are epigenetic enzymes that install acetyl groups onto lysine residues of cellular proteins such as histones, transcription factors, nuclear receptors, and enzymes. HATs have been shown to play a role in diseases ranging from cancer and inflammatory diseases to neur...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Wapenaar, Hannah, Dekker, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881052/
https://ncbi.nlm.nih.gov/pubmed/27231488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0225-2
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