NLRP3 Deficiency Reduces Macrophage Interleukin-10 Production and Enhances the Susceptibility to Doxorubicin-induced Cardiotoxicity

NLRP3 inflammasomes recognize non-microbial danger signals and induce release of proinflammatory cytokine interleukin (IL)-1β, leading to sterile inflammation in cardiovascular disease. Because sterile inflammation is involved in doxorubicin (Dox)-induced cardiotoxicity, we investigated the role of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kobayashi, Motoi, Usui, Fumitake, Karasawa, Tadayoshi, Kawashima, Akira, Kimura, Hiroaki, Mizushina, Yoshiko, Shirasuna, Koumei, Mizukami, Hiroaki, Kasahara, Tadashi, Hasebe, Naoyuki, Takahashi, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880937/
https://ncbi.nlm.nih.gov/pubmed/27225830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26489
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados