MCUR1 is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics

Mitochondrial Ca(2+) Uniporter (MCU)-dependent mitochondrial Ca(2+) uptake is the primary mechanism for increasing matrix Ca(2+) in most cell types. However, a limited understanding of the MCU complex assembly impedes the comprehension of the precise mechanisms underlying MCU activity. Here we repor...

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Udgivet i:Cell Rep
Main Authors: Tomar, Dhanendra, Dong, Zhiwei, Shanmughapriya, Santhanam, Koch, Diana A., Thomas, Toby, Hoffman, Nicholas E., Timbalia, Shrishiv A., Goldman, Samuel J., Breves, Sara L., Corbally, Daniel P., Nemani, Neeharika, Fairweather, Joseph P., Cutri, Allison R., Zhang, Xueqian, Song, Jianliang, Prado, Fabian J., Huang, Jianhe, Barrero, Carlos, Rabinowitz, Joseph E., Luongo, Timothy S., Schumacher, Sarah M., Rockman, Michael, Dietrich, Alexander, Merali, Salim, Caplan, Jeffrey, Stathopulos, Peter, Ahima, Rexford S., Cheung, Joseph Y., Houser, Steven R., Koch, Walter J., Patel, Vickas, Gohil, Vishal M., Elrod, John W., Rajan, Sudarsan, Madesh, Muniswamy
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880542/
https://ncbi.nlm.nih.gov/pubmed/27184846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.050
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