Alteration of a protease-sensitive region of Pseudomonas exotoxin prolongs its survival in the circulation of mice.

Pseudomonas exotoxin A (PE) is a single-chain 66-kDa polypeptide that kills eukaryotic cells by ADP-ribosylation of translational elongation factor 2. PE is composed of three major structural domains whose functions are binding of cells (I), translocation (II), and ADP-ribosylation (III). Here we de...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Brinkmann, U, Pai, L H, FitzGerald, D J, Pastan, I
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1992
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC48804/
https://ncbi.nlm.nih.gov/pubmed/1557414
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla