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Transforming growth factor alpha-Pseudomonas exotoxin fusion protein prolongs survival of nude mice bearing tumor xenografts.

Transforming growth factor alpha (TGF alpha)-Pseudomonas exotoxin 40 (PE40) is a chimeric protein consisting of an N-terminal TGF alpha domain fused to a C-terminal 40-kDa segment of the Pseudomonas exotoxin A protein. TGF alpha-PE40 exhibits the receptor-binding activity of TGF alpha and the cell-k...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Heimbrook, D C, Stirdivant, S M, Ahern, J D, Balishin, N L, Patrick, D R, Edwards, G M, Defeo-Jones, D, FitzGerald, D J, Pastan, I, Oliff, A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54184/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2352944/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4697
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