Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity.

Pseudomonas exotoxin (PE), a single-chain polypeptide toxin of 613 amino acids, consists of three functional domains: an amino-terminal receptor-binding domain, a middle translocation domain, and a carboxyl-terminal ADP-ribosylation domain. Deletion of as few as 2 or as many as 11 amino acids from t...

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Bibliografiske detaljer
Main Authors: Chaudhary, V K, Jinno, Y, FitzGerald, D, Pastan, I
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC53252/
https://ncbi.nlm.nih.gov/pubmed/2104981
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