Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity.
Pseudomonas exotoxin (PE), a single-chain polypeptide toxin of 613 amino acids, consists of three functional domains: an amino-terminal receptor-binding domain, a middle translocation domain, and a carboxyl-terminal ADP-ribosylation domain. Deletion of as few as 2 or as many as 11 amino acids from t...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53252/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2104981/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.308 |
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