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Chemical Synthesis of Hydrocarbon-Stapled Peptides for Protein Interaction Research and Therapeutic Targeting

The peptide alpha-helix represents one of Nature’s most featured protein shapes and is employed in a diversity of protein architectures, spanning the very cytoskeletal infrastructure of the cell to the most intimate contact points between crucial signaling proteins. By installing an all-hydrocarbon...

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Detalhes bibliográficos
Publicado no:Curr Protoc Chem Biol
Main Authors: Bird, Gregory H., Crannell, W. Christian, Walensky, Loren D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879976/
https://ncbi.nlm.nih.gov/pubmed/23801563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470559277.ch110042
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