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Challenges in Targeting a Basic Helix–Loop–Helix Transcription Factor with Hydrocarbon-Stapled Peptides
Basic helix–loop–helix (bHLH) transcription factors play critical roles in organism development and disease by regulating cell proliferation and differentiation. Transcriptional activity, whether by bHLH homo- or heterodimerization, is dependent on protein–protein and protein–DNA interactions mediat...
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| 出版年: | ACS Chem Biol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5534327/ https://ncbi.nlm.nih.gov/pubmed/27643505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00465 |
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