Novel diagnostic cerebrospinal fluid biomarkers for pathologic subtypes of frontotemporal dementia identified by proteomics

INTRODUCTION: Reliable cerebrospinal fluid (CSF) biomarkers enabling identification of frontotemporal dementia (FTD) and its pathologic subtypes are lacking. METHODS: Unbiased high-resolution mass spectrometry–based proteomics was applied on CSF of FTD patients with TAR DNA-binding protein 43 (TDP-4...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Teunissen, Charlotte E., Elias, Naura, Koel-Simmelink, Marleen J.A., Durieux-Lu, Sisi, Malekzadeh, Arjan, Pham, Thang V., Piersma, Sander R., Beccari, Tommaso, Meeter, Lieke H.H., Dopper, Elise G.P., van Swieten, John C., Jimenez, Connie R., Pijnenburg, Yolande A.L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
CSF Biomarkers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879654/
https://ncbi.nlm.nih.gov/pubmed/27239539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2015.12.004
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