Discriminative and prognostic potential of cerebrospinal fluid phosphoTau/tau ratio and neurofilaments for frontotemporal dementia subtypes

INTRODUCTION: A decreased cerebrospinal fluid (CSF) p-Tau(181) to total tau ratio (p/t-tau) is a biomarker for frontotemporal lobar degeneration with TDP43 inclusions (FTLD-TDP) and for amyotrophic lateral sclerosis (ALS). CSF light chain neurofilaments (NfL) are increased in ALS. We examined whethe...

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Publicado en:Alzheimers Dement (Amst)
Autores principales: Pijnenburg, Yolande A.L., Verwey, Nicolaas A., van der Flier, Wiesje M., Scheltens, Philip, Teunissen, Charlotte E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
Materias:
CSF Biomarkers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879490/
https://ncbi.nlm.nih.gov/pubmed/27239528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2015.11.001
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