Quantitative PPARγ expression affects the balance between tolerance and immunity

PPARγ modulates energy metabolism and inflammation. However, its specific functions in the balance of immunity in vivo have been explored incompletely. In this study, by the age of 14 mo, Pparg(C/−) mice with PPARγ expression at 25% of the normal level exhibited high autoantibody levels and develope...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Liu, Ya-Hui, Tsai, Yau-Sheng, Lin, Shih-Chieh, Liao, Nan-Shih, Jan, Ming-Shiou, Liang, Chung-Tiang, Hsu, Shih-Wen, Chen, Wen-Chung, Sung, Junne-Ming, Maeda, Nobuyo, Tsai, Pei-Jane
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879582/
https://ncbi.nlm.nih.gov/pubmed/27221351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26646
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